The study of the influence of technical and technological factors on the efficiency of well flushing was carried out under experimental conditions. The analysis of existing experimental installations is performed with the help of which it is possible to assess the influence of technical and technological factors on the process of well flushing. The laboratory facility for modeling the well flushing process was designed using similarity criteria obtained in accordance with the basic provisions of the theory of dimensions. The developed installation allows you to model and study the influence of many factors on the well flushing process due to its compact overall dimensions and ease of conducting experiments, namely: the eccentric placement of the drill string; the type of flushing fluid (rheological properties); the size of the rock fraction; the frequency of pulsations to create a pulsating character of the fluid movement; rotation of the drill string; longitudinal movement of the drill string. The main factors of influence and the range of their changes on the efficiency of sludge transportation are determined on the basis of previous studies. An experiment plan is constructed to study the significance of factors on the quality of sludge removal from the well bore using the «Taguchi» plan. Data processing was performed in the software «Mathcad Prime». Variations in factors lead to an improvement in the quality of well flushing, by reducing the area of sludge settling in the wellbore. The flow rate of the washing liquid has the most positive effect on the removal of sludge. The size of the rock fraction and the longitudinal movement of the drill string has the least impact. Pulsation of the washing liquid has a significant impact on the quality of sludge removal, which is a significant and interesting factor from the point of view of further scientific research